Cooperations between TRAIN partners brought about new centres and institutions via support of the Niedersächsisches Ministerium für Wissenschaft und Kultur (MWK). These translational centres connect the research structures of the TRAIN partners and close the gap between basic science and clinical practice - for a complete biomedical development chain in Lower Saxony.
At the Braunschweig Systems Biology Centre BRICS, the TU Braunschweig, the HZI and the Leibniz Institute DSMZ combine their competencies in the field of infections, generation of active ingredients and biotechnology. The aim is to measure and model complex biological processes in a holistic way through the interplay of biological experiments and mathematical models, thus making it easier to understand these processes. In collaboration with the TRAIN partners, this expertise is used as the basis for the entire translation process.
The BMWZ (Biomolekulares Wirkstoffzentrum) is a multidisciplinary research institute based in the faculty of science at the Leibniz Universität Hannover. It brings together skills in organic chemistry, structural biology, natural products chemistry, biosynthesis and medicinal chemistry with the aim of understanding and exploiting the synthesis, biosynthesis and mechanism of action of biologically active compounds isolated from nature. The BMWZ building accommodates around 100 researchers drawn from research groups of the University of Hannover including the Institute for Organic Chemistry (OCI), the Institute for Technical Chemistry (TCI) and the Institute of Biophysics. External groups include members from the Helmholtz Centre for Infection Research (HZI) in Braunschweig, the Helmholtz Zentrum München (HMGU), and the Hannover Medical Scholol (MHH) among others.
The CRC Hannover, which opened in 2014, maximizes benefits for patients by enabling leading academic experts to pool their expertise and collaborate. Three legally independent research organizations are working at the CRC Hannover under one roof. While clinical investigators of Fraunhofer ITEM and the Hannover Medical School perform early-phase clinical trials of new drugs and medical devices, researchers of the Helmholtz Centre for Infection Research are conducting a part of Germany’s largest health study, known as “German National Cohort study”. What unites the three partners is their dedication to becoming one of Europe’s leading centers for patient-oriented translational medicine.
The Center for Pharmaceutical Process Engineering (PVZ) is an interdisciplinary research centre of the TU Braunschweig. The aim of the PVZ is to research innovative processes for the cost-effective production of effective and individualised pharmaceutical products. In order to achieve this goal, competences of the different disciplines - pharmacy, engineering sciences, micro- and process engineering - are bundled in an interdisciplinary approach. In the research projects of the PVZ, scientists from the TU Braunschweig, the University of Hannover, the HAWK Göttingen, the TU Clausthal and the HZI work closely together to further develop pharmaceutical products using a synergistic approach.