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New diagnostic approach for meningoencephalitis by biomarkers

Wissenschaftler des TWINCORE konnten zeigen, dass Infektionen mit dem Varizelle zoster Virus von einem ganz charakteristischen Spektrum an Stoffwechselprodukten im Hirnwasser begleitet werden, durch das sich VZV Infektionen von vergleichsweise harmlosen Enteroviren zuverlässig unterscheiden lassen. Die Forscher der Arbeitsgruppe Biomarker für Infektionskrankheiten veröffentlichten ihre Ergebnisse kürzlich im Journal of Neuroinflammation und legten damit den Grundstein für einen neuen, schnelleren diagnostischen Ansatz bei Meningoenzephalitis.

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A new piece in the puzzle of how herpesviruses outwit the immune system

HZI researchers have uncovered how a cancer-causing virus specifically targets a protein of its host to successfully establish infection

Humans are constantly exposed to pathogens like bacteria and viruses. In most cases, the immune system successfully detects and eliminates these invaders. However, the herpesvirus family has adapted brilliantly to the immune system: its members manage to stay in the host’s body for life after infection. A research team at the Helmholtz Centre for Infection Research (HZI) recently discovered that a protein of the carcinogenic Kaposi’s sarcoma-associated herpesvirus (KSHV) commandeers an immune system component for its own benefit. This enables the virus to successfully infect its host. The researchers have published their results in the peer-reviewed journal PLOS Pathogens.

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New treatment approach for hepatitis E infections in pregnant women

Hepatitis E virus infections are usually subclinical and are considered as an underrated disease by physicians. The number of infections worldwide is estimated at 20 million infected people per year. In our latitudes, primarily people with weakened immune systems get sick. In Asia and Africa, however, a different genotype is present, which is a serious threat to a very special population group: pregnant women.

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The TRAIN Academy sent off the first graduates

On October 26 the first graduates finished their education Programme: Prof. Christopher Baum and the Scientific Director of the HZI, Prof. Dirk Heinz, presented the certificates to the eight graduates.

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